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Restasis (Cyclosporine) Opthalmic Emulsion 

What is Restasis? 

Restasis is a prescription eye drop used to treat Chronic Dry Eye in patients whose tear production is presumed to be suppressed due to ocular inflammation. Dry eye occurs when tears fail to provide adequate lubrication for the eyes. This causes irritation, redness, burning/stinging, itchiness, blurred vision, and sensation of having something in the eye. Restasis Ophthalmic Emulsion helps increase tear production which may be reduced by inflammation due to Chronic Dry Eye. It is thought to work by suppressing inflammation that may be preventing normal tear secretion. 

What is Chronic Dry Eye? 

Chronic dry eye is a condition in which the eye does not produce enough tears to stay lubricated. It is caused by problems with the tear glands not producing enough tears or the tears evaporating too quickly. Symptoms include persistent dryness, irritation, burning, scratchiness, and blurry vision. If left untreated, chronic dry eye can lead to damage to the surface of the eye. It is typically treated with artificial tears/eye drops, ointments, warm compresses, and medications. Lifestyle changes like hydration, managing screen time, and avoiding smoke can also help manage chronic dry eye. 

How to use Restasis? 

Use Restasis exactly as prescribed by your doctor. The recommended dosage is one drop instilled in each eye, twice a day- approximately 12 hours apart. 

Follow these steps when using Restasis: 

Thoroughly wash your hands before each use. This prevents contaminating the bottle tip and solution. 

Tilt your head back and pull down your lower eyelid to form a small pocket. 

Gently squeeze the bottle to release one drop into the pouch, taking care does not to touch the eye, eyelid or any surface with the bottle tip. Do not blink or close your eyes. 

Let go of the lower lid and gently close your eyes for 2-3 minutes. This allows the eye drops to be absorbed. 

Repeat the process for the other eye if prescribed for both eyes. 

Replace cap securely after use. 

Avoid touching the bottle tip to any surface to prevent contamination and potential eye infections. 

Wait at least 15 minutes after using the drops before inserting contact lenses. The preservative chlorine dioxide can be absorbed by soft contact lenses. 

Do not wear contact lenses if your eyes are red or irritated. 

It may take up to 6 months before you see the full benefit of using Restasis. Therefore, it is important to use it exactly as prescribed by your doctor. Do not use more than the recommended dose even if your symptoms worsen. Notify your doctor if your condition persists or worsens. 

Restasis Opthalmic Emulsion Ingredients

Active Ingredient: cyclosporine 0.05% 

Inactive Ingredients: castor oil, polysorbate 80, carbomer copolymer type A, glycerin, sodium hydroxide, purified water. 

Preserved with chlorine dioxide, which may be absorbed by soft contact lenses. 

Warnings and Precautions 

Restasis may increase your risk of infections or cancer. Immediately contact your doctor if you develop any signs of infection or illness. 

There is a greater chance of developing eye infections and swelling while using Restasis. Seek medical care if you notice any eye redness, vision changes, pain or discharge. 

Allergic reactions may occur with Restasis. Stop using the medication and notify your doctor immediately if you experience rash, itching, severe redness, swelling or trouble breathing. 

Use caution when driving or performing hazardous tasks as Restasis may cause blurred vision after application. Wait until your vision clears before driving or using machinery. 

Restasis is not recommended for use in children under 16 years. 

Advise your doctor if you are pregnant, planning pregnancy or are breastfeeding. The risks and benefits should be discussed. 

Restasis Interactions  

Inform your doctor about all medicines you use, including other eye drops, prescriptions, over-the-counter medications, vitamins and herbal products. Restasis may interact with other drugs. For instance, using Restasis with immunomodulating drugs like methotrexate can increase risk of immune system effects. The following drugs may potentially interact with Restasis: 

• Immunosuppressants 
• Allergy shots 
• Antifungals 
• Antibiotics 
• Antivirals 
• Anti-seizure medicines 
• Cancer chemotherapy 

What are the Side Effects of Restasis? 

The most commonly reported side effects of Restasis are: 

• Eye irritation (burning, stinging, redness, itching, pain) 
• Eye discharge 
• Uncomfortable feeling in the eye 
• Blurred vision 
• Increased tearing or watery eyes 
• Light sensitivity 
• Eye swelling 
• Eye infection or inflammation 
• Feeling like something is in the eye 

Rare but serious side effects may include severe allergic reaction (anaphylaxis), eye injury or swelling, macular edema. Seek urgent medical care if you experience any serious reactions like rash, itching, severe redness, trouble breathing or swallowing, chest tightness, or eye pain/changes in vision. 

Contact your doctor if you experience any bothersome side effects. Do not discontinue using Restasis before consulting your doctor. 

Why is Restasis so Expensive? 

The price of the Restasis may be expensive due to various factors such as your location, prescribed dosage, and the extent of your insurance coverage. To avail of financial benefits, buy Restasis at its most affordable online rate and have your medication conveniently shipped to your address. 

Resources

1. Important Safety Information 

1. Full Product Information 

1. Take the Chronic Dry Eye Quiz 

1. Chronic Dry Eye 

Frequently Asked Questions (FAQs)

How does Restasis work to treat dry eyes? 

Restasis contains the active drug cyclosporine which is thought to suppress inflammation that reduces tear secretion in chronic dry eyes. By inhibiting inflammation, it helps increase tear production which lubricates the eyes and relieves dry eye symptoms. 

How long does it take for Restasis to work? 

You may start feeling improvement in dry eye symptoms within 4 weeks. But it can take up to 6 months of continued use for Restasis to reach its full effect. So it is important to use it regularly twice a day as prescribed. 

Can I use Restasis along with artificial tears? 

Yes, you can use artificial tears to supplement the effects of Restasis if needed for additional lubrication and comfort. Use artificial tears at least 15 minutes before or after using Restasis. 

What should I do if I miss a dose of Restasis? 

If you forget to use your Restasis eye drops, skip the missed dose completely and just continue with your regular schedule. Do not use two doses together to make up for a missed one. 

How do I properly store Restasis? 

Store Restasis at room temperature away from moisture, heat and light. Do not freeze. Keep the bottle tightly closed when not in use. Discard the medication after 28 days from first opening the bottle. 

Is Restasis safe to use if I wear contact lenses? 

No, do not wear contact lenses while using Restasis drops. The preservative chlorine dioxide can be absorbed into soft lenses. Wait at least 15 minutes after Restasis before inserting contacts. Speak to your eye doctor about contact lens wear while using this medication.