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Levitra (Vardenafil) 

What is Levitra? 

Levitra is an oral prescription medication used to treat erectile dysfunction (ED) in adult men. It belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors that improve blood flow to the penis to help achieve and maintain an erection during sexual stimulation. 

Levitra contains the active ingredient vardenafil HCl, which prevents the action of PDE5, an enzyme that breaks down cGMP. cGMP causes the smooth muscle cells in the penis to relax, allowing increased blood flow. Levitra enhances the effects of cGMP, allowing cGMP to accumulate and improve erections. 

Levitra comes in tablet form, typically taken in doses of 5mg, 10mg, and 20mg. It is taken as needed approximately 60 minutes before sexual activity. One tablet per day is the recommended dosage. Levitra can be taken with or without food. 

What is erectile dysfunction (ED)?  

Erectile Dysfunction (ED) is when a man has trouble getting or keeping an erection for sex. It can happen because of physical issues like problems with blood flow, nerves, or hormones. Psychological factors like stress, anxiety, and relationship problems can also play a role. 

How to use Levitra (Vardenafil)? 

The recommended starting dose is 10mg taken orally approximately 60 minutes before sexual activity. Based on efficacy and tolerability, the dose may be increased to 20mg or decreased to 5mg. Do not exceed more than one dose in a 24-hour period. 

Take Levitra tablets whole with water. Do not chew, crush, or split the tablets. If taking Levitra with food, avoid high-fat meals which can delay absorption and reduce effectiveness. Allow at least 24 hours between Levitra doses. 

Ingredients 

Active ingredient: Vardenafil HCl  

Inactive ingredients: colloidal silicon dioxide, crospovidone, hydroxypropyl methylcellulose, iron oxide, magnesium stearate, microcrystalline cellulose, polyethylene glycol, titanium dioxide. 

Warnings and Cautions 

Do not take Levitra with medications containing nitrates, medications used to treat angina, or nitroglycerin medications, as the combination may cause an unsafe drop in blood pressure. 

Inform your doctor if you have conditions like liver disease, kidney disease, bleeding disorder, heart disease, blood cell disorder, stomach ulcer, retinitis pigmentosa, or physical deformity of the penis. 

Avoid heavy alcohol consumption (more than 5 glasses of wine or 5 shots of whiskey) when taking Levitra as it can increase the risks of side effects. 

Grapefruit juice may increase Levitra levels in the blood and should be consumed in moderation. 

Levitra does not protect against sexually transmitted infections or pregnancy. Use condoms. 

Elderly patients may be more sensitive to side effects and require dose adjustments. 

Interactions 

Levitra may interact with the following: 

• Nitrates/nitroglycerin – risk of severe low blood pressure 
• Alpha-blockers like doxazosin or tamsulosin – increased risk of dizziness/low BP 
• Azole antifungals like ketoconazole or itraconazole – higher Levitra levels 
• HIV protease inhibitors – higher Levitra levels 
• Macrolide antibiotics like erythromycin or clarithromycin – higher Levitra levels 

• Other PDE5 inhibitor ED drugs like sildenafil or tadalafil 
• High blood pressure medications 

Side Effects 

Common side effects (affecting 1-10% of users) include headache, flushing, nasal congestion, dyspepsia, dizziness, and back pain. 

Rare but serious side effects requiring medical attention: 

• Priapism – prolonged, painful erection lasting over 4 hours 
• Vision changes like loss of vision or NAION 
• Hearing problems like sudden decrease or loss of hearing 
• Allergic reaction – rash, hives, swelling, difficulty breathing 
• Chest pain 

Please consult the Patient Information Leaflet or ask your doctor for more safety information. Report any concerning side effects immediately when taking Levitra. 

Frequently Asked Question (FAQ)

How long does Levitra last? 

The effects of Levitra may last up to 5 hours. It varies between individuals based on metabolism and other factors. 

Can I drink alcohol while taking Levitra?

You should avoid drinking large amounts of alcohol while taking Levitra, as it can increase the risk of side effects. Moderation in alcohol intake should not cause issues. Consult your doctor for specific guidance. 

How soon before sex should I take Levitra? 

Levitra should be taken approximately 60 minutes before sexual activity for the best results. Depending on the individual, it may take between 25-60 minutes to start working. 

What should I do if Levitra stops working? 

If you find Levitra is no longer effective, speak to your doctor. They may adjust your dosage or switch you to an alternative medication. Do not increase the dose or frequency without medical approval. 

Is Levitra safe to use long-term? 

Yes, Levitra is generally safe for long-term use as prescribed by a doctor. Do not take more than the recommended dosage and report any concerning side effects to your healthcare provider.