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Dexilant (Dexlansoprazole)Â
What is Dexilant?Â
Dexilant is a prescription medicine used to treat certain stomach and esophagus problems (such as acid reflux). It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. Dexilant helps heal acid damage to the lining of the esophagus, prevents ulcers, and reduces the risk of hospitalization for complications from acid reflux.Â
Dexilant belongs to a class of drugs called proton pump inhibitors (PPIs). It works by decreasing the amount of acid made in the stomach.Â
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How to use Dexilant?Â
Take Dexilant exactly as prescribed by your doctor. The recommended dosage is one 60 mg delayed release capsule, once daily, at least 1 hour before a meal. The capsule should be swallowed whole – do not chew or crush.Â
Treatment with Dexilant usually lasts 4 to 8 weeks. Long-term and multiple daily dose therapy is not recommended.Â
Dexilant may be taken with antacids if needed.Â
IngredientsÂ
Active ingredient: dexlansoprazole (as dexlansoprazole modified release pellets).Â
Inactive ingredients: sugar spheres, magnesium carbonate, sucrose, low-substituted hydroxypropyl cellulose, titanium dioxide, hydroxypropyl cellulose, hypromellose 2910, talc, methacrylic acid copolymers, polyethylene glycol 8000, triethyl citrate, polysorbate 80, and colloidal silicon dioxide.Â
CautionsÂ
Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Dexilant may harm an unborn baby.Â
Use caution if you have liver problems or low magnesium levels in your blood.Â
Dexilant may increase your risk of bone fractures, especially with long-term use at high doses.Â
Long-term PPI use may lead to low vitamin B12 levels. Talk to your doctor about vitamin supplementation.Â
Stop taking Dexilant and tell your doctor if you experience severe diarrhea.Â
InteractionsÂ
Tell your doctor about all medications you take, including prescription and over-the-counter drugs, vitamins, and herbal supplements. Dexilant may interact with the following:Â
- Anticoagulants like warfarin – Increased risk of bleedingÂ
- Methotrexate – Increased blood levels, greater risk of side effectsÂ
- Tacrolimus – Increased blood levels, greater risk of side effectsÂ
- Clopidogrel – Decreased effectivenessÂ
- St. John’s Wort – Decreased Dexilant effectivenessÂ
What are the Side Effects of Dexilant?Â
Common side effects of Dexilant include:Â
- Headache, abdominal pain, nausea, diarrhea, vomitingÂ
- Respiratory infections, cough, sore throatÂ
- Gas, constipationÂ
Call your doctor if you experience severe or concerning side effects including:Â
- Rash, itching, swelling, dizziness, breathing problemsÂ
- Unusual changes in mood/behavior, anxiety, depressionÂ
- Muscle pain or weakness, bone painÂ
- Severe diarrhea, stomach pain/cramping, blood in stoolÂ
- Blurred vision, eye pain/swellingÂ
Frequently Asked Question (FAQ)
How long does it take for Dexilant to work?Â
Dexilant starts working in about an hour, but its full effect may take 1-4 days. You may need to take it for 2-4 weeks for full benefits.Â
Can I cut or crush the Dexilant capsule?Â
No, do not cut, crush or chew the capsule. It is coated to protect the stomach, and must be swallowed whole.Â
Can I take Dexilant with food?Â
Take it at least one hour before a meal for best absorption. You can take antacids with it if needed.Â
How long should I take Dexilant?Â
Take it exactly as prescribed, usually 4-8 weeks. Do not take it long-term without doctor supervision.Â
What should I avoid while taking Dexilant?Â
Avoid alcohol and NSAIDs like aspirin or ibuprofen, as they can increase your risk of stomach bleeding. Also avoid St. John’s Wort and certain antifungal drugs.Â
Can I take Dexilant while pregnant or breastfeeding?
Use caution, as Dexilant may harm a developing baby. Discuss with your doctor regarding risks vs. benefits.



